The role of TNF? in type2 diabetes mellitus

Type2 Diabetes mellitus is a chronic and most common form of diabetes characterized by hyperglycemia arising from problems with the utilization or production insulin. Various agents related to an increased risk developing T2DM include pro-inflammatory cytokines that are critically associated progressive resistance insulin pathogenesis newly diagnosed T2DM. The study aimed possible association TNF? serum level in type2 initiation using enzyme-linked immunosorbent assay (ELISA). In this study, 50 patients age range between 25 70 years were included; addition fifty healthy volunteers whose sex matched patient’s group act as control, samples collected estimate levels Enzyme-Linked Immunosorbent Assay revealed statistically significantly higher compared control group. On other hand, there no significant difference obese non-obese may have role development current showed type 2 DM, studied marker might help prediction Keywords. T2DM, TNF?, ELISA